ISO 13344:2015 provides a means for estimating the lethal toxic potency of the fire effluent produced from a material while exposed to the specific combustion conditions of a physical fire model. The lethal toxic potency values are specifically related to the fire model selected, the exposure scenario and the material evaluated.

Lethal toxic potency values associated with 30-min exposures of rats are predicted using calculations which employ combustion atmosphere analytical data for carbon monoxide (CO), carbon dioxide (CO2), oxygen (O2) (vitiation) and, if present, hydrogen cyanide (HCN), hydrogen chloride (HCl), hydrogen bromide (HBr), hydrogen fluoride (HF), sulfur dioxide (SO2), nitrogen dioxide (NO2), acrolein and formaldehyde. The chemical composition of the test specimen may suggest additional combustion products to be quantified and included. If the fire effluent toxic potency cannot be attributed to the toxicants analysed, this is an indication that other toxicants or factors must be considered.

ISO 13344:2015 is applicable to the estimation of the lethal toxic potency of fire effluent atmospheres produced from materials, products or assemblies under controlled laboratory conditions and should not be used in isolation to describe or appraise the toxic hazard or risk of materials, products or assemblies under actual fire conditions. However, results of this test may be used as elements of a fire hazard assessment that takes into account all of the factors which are pertinent to an assessment of the fire hazard of a particular end use; see ISO 19706.

The intended use of fire safety-engineering calculations is for life-safety prediction for people and is most frequently for time intervals somewhat shorter than 30 min. This extrapolation across species and exposure intervals is outside the scope of ISO 13344:2015.

ISO 13344:2015 does not purport to address all of the safety problems associated with its use. It is the responsibility of the user of ISO 13344:2015 to establish appropriate safety and health practices.